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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PTPN20A
All Species:
20.61
Human Site:
T346
Identified Species:
64.76
UniProt:
Q4JDL3
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q4JDL3
NP_001035816.1
420
48423
T346
Y
A
R
K
S
H
L
T
G
P
M
V
V
H
C
Chimpanzee
Pan troglodytes
XP_001136909
653
73228
T579
Y
A
R
K
S
H
L
T
G
P
M
V
V
H
C
Rhesus Macaque
Macaca mulatta
XP_001109336
420
48468
T346
Y
A
R
K
S
H
L
T
G
P
M
V
V
H
C
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
O55082
426
49100
T352
Y
V
R
K
S
H
I
T
G
P
L
L
V
H
C
Rat
Rattus norvegicus
A1L1L3
421
48562
T347
Y
V
R
K
S
H
I
T
G
P
L
L
V
H
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515862
889
97591
S806
Y
M
R
H
I
H
T
S
G
P
I
I
T
H
C
Chicken
Gallus gallus
XP_001234615
841
94302
R765
Y
M
R
K
A
H
R
R
G
P
V
V
A
H
C
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001185050
396
44869
P326
R
I
H
D
D
R
L
P
I
V
V
H
C
S
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
64
93.5
N.A.
N.A.
64.3
66
N.A.
23.8
25.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
33.3
Protein Similarity:
100
64.3
96.6
N.A.
N.A.
77
79.3
N.A.
33.5
37.4
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
53.3
P-Site Identity:
100
100
100
N.A.
N.A.
73.3
73.3
N.A.
46.6
60
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
N.A.
N.A.
93.3
93.3
N.A.
66.6
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
38
0
0
13
0
0
0
0
0
0
0
13
0
13
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
13
0
88
% C
% Asp:
0
0
0
13
13
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
88
0
0
0
0
0
0
% G
% His:
0
0
13
13
0
88
0
0
0
0
0
13
0
88
0
% H
% Ile:
0
13
0
0
13
0
25
0
13
0
13
13
0
0
0
% I
% Lys:
0
0
0
75
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
50
0
0
0
25
25
0
0
0
% L
% Met:
0
25
0
0
0
0
0
0
0
0
38
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
13
0
88
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
13
0
88
0
0
13
13
13
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
63
0
0
13
0
0
0
0
0
13
0
% S
% Thr:
0
0
0
0
0
0
13
63
0
0
0
0
13
0
0
% T
% Val:
0
25
0
0
0
0
0
0
0
13
25
50
63
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
88
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _